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Otsuka’s Sibeprenlimab Demonstrates Meaningful Outcomes in Phase III Study for Immunoglobulin A Nephropathy
In the Phase III VISIONARY study, sibeprenlimab, an investigational monoclonal antibody, showed a 51.2% reduction in ...
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Phase III IRAKLIA and Phase II IZALCO Trials Support Sarclisa On-Body Delivery for Relapsed/Refractory Multiple Myeloma
New data from the IRAKLIA and IZALCO trials, presented at the 2025 ASCO Annual Meeting, demonstrate that subcutaneous ...
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Overcoming Operational Challenges in Oncology Clinical Trials: Lessons from a Multicentric Study in India
Case study highlights how clinical operations teams can overcome complex regulatory and operational hurdles to finish a trial ...
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CARTITUDE-1 Trial Shows Carvykti Achieves Durable, Treatment-Free Remissions in Relapsed or Refractory Multiple Myeloma
Results from the Phase Ib/II CARTITUDE-1 trial demonstrated that a single infusion of Carvykti delivered durable, ...
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HHS Cancels Moderna Grant for Late-Stage Development of mRNA Vaccine Candidate
Despite positive results from a Phase I/II trial of its investigational pandemic influenza vaccine, mRNA-1018, Moderna’s ...
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How Trump’s Most Favored Nation Policy Could Impact Funding for Clinical Development
In this video interview, Jim Kremidas, executive director, Association for MultiSite Research Corporations (AMRC), discusses ...
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Phase III MATTERHORN Trial Shows Imfinzi Combo Significantly Improves Event-Free Survival in Resectable Gastric and GEJ Cancers
Interim results from the global MATTERHORN study mark the first time an immunotherapy has demonstrated statistically ...
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Tecentriq and Zepzelca Combo Demonstrates Significant Survival Benefit in Phase III Study for Extensive-Stage Small Cell Lung Cancer
In the Phase III IMforte trial, Tecentriq (atezolizumab) and Zepzelca (lurbinectedin) reduced the risk of disease progression ...
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Phase III BREAKWATER Trial Shows Braftovi-Based Regimen Improves Survival in BRAF V600E-Mutant Metastatic Colorectal Cancer
Phase III data presented at ASCO 2025 and published in The New England Journal of Medicine show that Pfizer’s Braftovi (encorafenib), combined with Erbitux (cetuximab) and mFOLFOX6, significantly ...