Buffalo Bills' offensive success: How they dominated the 49ers + Matt Milano’s return & more!

The U.S. government has closed its investigation into the outbreak tied to slivered onions in Quarter Pounders.

LOCKPORT, N.Y. — New York State Police shared on Tuesday troopers in Lockport arrested four teens after a stolen vehicle ...

BUFFALO, N.Y. — While the lake effect storm over the weekend wasn't the worst inch, or 18, that Buffalo has ever seen, it was ...

BUFFALO, N.Y. — Buffalo Police are investigating an incident that occurred at a neighborhood favorite: Gene McCarthy's Old ...

Buffalo mayoral candidate Garnell Whitfield sits down to talk about bringing change, addressing housing issues, and ...

The city's financial overseer produces the report annually to provide a "snapshot" of trends over the past 5 years and inform ...

President and CEO of Buffalo Museum of Science Gary Siddall and Dr. Holly Schreiber joined Most Buffalo in studio Tuesday to ...

TONAWANDA, N.Y. — On Tuesday, hundreds of former Sumitomo Rubber Plant employees met with potential employers at a big job ...

Many common grocery items have doubled in cost since the turn of the century, leaving some families to have to make tough ...

In addition to providing holiday entertainment, EverHaunt is also focusing on giving back to the community during the season ...

BUFFALO, N.Y. — A Buffalo man has been sentenced to 25 years to life in prison for killing his girlfriend last year. Savon R.