Single-cell transcriptomics data from mouse bone-relevant cells was used to inform human bone mineral density genome-wide association studies and prioritize genetic targets with potential causal roles ...
A Coma Pattern-Based Autofocusing Method Resolves Bacterial Cold Shock Response at Single-Cell Level
Imaging-based single-cell physiological profiling holds great potential for uncovering fundamental bacterial cold shock response (CSR) mechanisms, but its application is impeded by severe focus drift ...
Mammalian oocytes utilize a conserved combination of cell cycle control, cytoskeletal organization, and polarity pathways that are fundamentally shared with other vertebrates and invertebrates.
The study showcases a significant and important enhancement of the MAGIC transgenesis method, by extending it genome-wide to all chromosomes. The authors provide compelling evidence to demonstrate ...
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, United States College of Health Solutions, Arizona State University, Phoenix, United States ...
It provides convincing evidence that demographic-specific functional templates improve functional neuroimaging studies that use hyperalignment. This study will be of interest to cognitive ...
Y-complex nucleoporin, Nup107, can regulate ecdysone production by affecting the transcription of Halloween genes and levels of RTK receptor, torso, for the metamorphic transition from larva to pupa.
Division of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States Division of Infectious Disease and Vaccinology, ...
EPB41L4A-AS1, a highly expressed snoRNA host long noncoding RNA, has multiple functions, positive regulation in cis of the EPB41L4A gene and a trans-acting role in supporting proper nucleolar biology.
This useful study supplements previous publications of willed attention by addressing a frontoparietal network that supports internal goal generation. The evidence is solid in analyzing two datasets ...
To enable more accurate estimation of connectivity, we propose a data-driven and theoretically grounded framework for optimally designing perturbation inputs, based on formulating the neural model as ...
This study presents valuable findings for identifying biotypes of depression patients using white matter measures, which are under-utilised and under-appreciated in current biological and ...
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