The Bills are a Super Bowl contender and the 49ers somehow probably aren’t even a playoff team. That’s how Sunday night’s ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

This week, Nick Bosa was asked about the 49ers' upcoming opponent, Bills quarterback Josh Allen. Here's what Bosa said. Q: ...

The San Francisco 49ers fell to 5-6 on the season in losing to the Green Bay Packers on Sunday. Top takeaways with Brock ...

The San Francisco 49ers are up against the Buffalo Bills in Week 13. The 49ers have dealt with an array of injuries this ...

The San Francisco 49ers will be missing two of their best players in their must-win matchup against the Green Bay Packers ...

The San Francisco 49ers will be without their starting quarterback and their best defensive player when they visit the Green ...

First comes Brock Purdy, the team's star quarterback, who missed Week 12 with a right shoulder. While Purdy is still ...

The San Francisco 49ers hosted a fan-focused event with the 49ers Pride Fan Group and PLUS (LGBTQ+) ERG to discuss being out ...

Wide receiver Chris Conley, linebacker Curtis Robinson and more San Francisco 49ers players shared what they're most grateful ...

The San Francisco 49ers are expecting to get star tight end George Kittle back this week for a key game against Green Bay, ...

San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...