The Houston Police Department, the Mayor's office, and the District Attorney's Office are teaming up for a holistic approach to battle the weed-eating rodents.

HPD plans to destroy hundreds of thousands of pounds of unneeded drugs and other evidence that have caused rat infestations and property room overflow

A rat infestation in a property room holding 1.2 million pieces of evidence is sparking concerns. "Anytime evidence is compromised, then cases could be compromised," a defense attorney said.

"Just one example, we've got 400,000 pounds of marijuana in storage that the rats are the only ones enjoying," Mayor John Whitmire said.