The Buffalo Bills clinched their record fifth consecutive AFC East title Sunday night after defeating the 49ers 35-10 on ...

NFL Week 13 closes with Sunday Night Football as the San Francisco 49ers visit Highmark Stadium and the Buffalo Bills. Time ...

San Francisco 49ers running back Jordan Mason is going on injured reserve, head coach Kyle Shanahan announced.

Lake-effect snow continued to fall on parts of western New York that were already blanketed with a foot or more over the past ...

Bills quarterback Josh Allen and head coach Sean McDermott celebrated by making snow angels after Buffalo clinched its fifth ...

Parts of the Great Lakes region saw new snow Monday and faced the prospect of even more this week after U.S.

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San ...

The first big snowfall of the season has blanketed parts of New York, Pennsylvania and Michigan during the busy holiday ...

Officials in upstate New York counties have declared a state of emergency as they prepare for a major snowstorm that has ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday night, winning 35-10 in Highmark Stadium in Orchard Park, N.Y.