Genome-wide association studies (GWAS) have catalogued hundreds of thousands of genetic variants linked to complex human traits and diseases, with more than 625,000 variant-trait associations across ...

Genetically predicted lower systolic blood pressure (SBP) seems to increase susceptibility to allergic rhinitis (AR), ...

Researchers led by Dr. W. David Hill at the University of Edinburgh have identified a significant genetic correlation between childhood cognitive function and longevity, providing the first molecular ...

Study reveals that BMI plays a crucial role in disease development, with genetic links to conditions like fatty liver disease disappearing when BMI is considered. Study: Sequence variants associated ...

LDlink is an interactive and powerful suite of web-based tools for querying germline variants in human population groups of interest to generate interactive tables and plots. All population genotype ...

This study presents a useful new approach for efficient computation of statistics on correlations between genetic variants (linkage disequilibrium, or LD), which the authors apply to quantify the ...

Abstract: Single nucleotide variants (SNVs) are very common in human genome and pose a significant effect on cellular proliferation and tumorigenesis in various cancers. Somatic variant and germline ...

Controlling the type I error rate while retaining sufficient power is a major concern in genome-wide association studies, which nowadays often examine more than a ...