Background Injured or reactive biliary epithelial cells participate in most chronic liver injuries in a process referred to as ductular reaction, which involves multicellular interactions with marked ...
Among the 321 million surgeries performed globally each year, sevoflurane dominates the inhaled anesthesia field due to its unique pharmacological properties. However, studies indicate that ...
Narcolepsy type 1 is a disorder of hypersomnolence caused by a loss of orexin neurons, which results in low orexin levels in the brain. In this phase 2, randomized, placebo-controlled trial, ...
The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 31 (August 2, 2022), pp. 1-8 (8 pages) The bacteria-derived formyl peptide fMet-Leu-Phe (fMLF) is a ...
We report here the first three‐dimensional structure of the type 1 inositol 1,4,5‐trisphosphate receptor (IP 3 R). From cryo‐electron microscopic images of purified receptors embedded in vitreous ice, ...
Inositol 1,4,5-Trisphosphate Receptor-Interacting Protein-Like 1 (ITPRIPL1), a single-pass type I membrane protein located in the membrane, functions as an inhibitory ligand of CD3ε. Recent studies ...
If you’re not familiar with inositol, it’s time to change that, as it may provide some surprising health benefits. For starters, it’s helpful to know inositol is a carbohydrate that naturally exists ...
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