The genomes of influenza viruses consist of multiple segments of single-stranded negative-sense RNA. Each of these segments is bound by the heterotrimeric viral RNA-dependent RNA polymerase and ...

Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer. PLOS Pathogens , 2019; 15 (10): e1008034 DOI: 10.1371/journal.ppat.1008034 Cite This Page : ...

The overall goal of this project is to identify new therapies that target influenza virus replication. The global health burden of annual influenza epidemics coupled with the emergence of highly ...

Polymerase component: PB1–PA interaction Polymerase function (e.g., T-705*) ... Contained within this matrix shell is the viral RNA genome, which (for influenza A viruses) ...

This article describes the structure of the influenza A virus. ... Each vRNA segment forms a helical hairpin in shape, and is bound by the heterotrimeric RNA polymerase complex.

Purdue University researchers now have developed an innovative, paper-based diagnostic test for rapidly detecting avian ...

To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilising its genome, made up of eight RNA 1 molecules.

“This breakthrough paves the way for the design of new drug molecules capable of binding to the protein coat, weakening viral RNA, and inhibiting replication of the influenza virus, whose ...

To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, which is made up of eight RNA molecules.

To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, made up of eight RNA molecules.

A reverse-transcriptase–polymerase-chain-reaction (RT-PCR) test specific for influenza A(H5) 2 was positive on the day of admission. The patient had signs of respiratory deterioration — chest ...