An 82-year-old woman with a history of congestive heart failure was admitted to this hospital for volume overload. Ascites, ...

In the phase 3 EMBARK trial, enzalutamide plus leuprolide and enzalutamide monotherapy were associated with longer metastasis ...

Patients with muscle-invasive bladder cancer have varied outcomes after cystectomy. Circulating tumor DNA (ctDNA)–based ...

Patients with previously untreated, locally advanced, unresectable or metastatic triple-negative breast cancer who are not ...

Geographic atrophy due to age-related macular degeneration (AMD) is the leading cause of irreversible blindness and affects more than 5 million persons worldwide. No therapies to restore vision in ...

The resident presented a patient admitted for chest pain after walking his dog. The attending asked, “What was the name of his dog?” The resident was stumped. Four years later, he’s not sure anything ...

A 43-year-old woman with bipolar disorder and advanced HIV infection was admitted to this hospital because of depressed mood, suicidal ideation, cough, and a temperature of 39.5°C. A diagnosis was ...

The concept of adjuvant therapy for cancer was developed at a time when systemic cancer treatment was limited to cytotoxic chemotherapy that could only be administered intermittently but rarely ...

Limited data are available on survival outcomes after sentinel-lymph-node biopsy alone as compared with lymphadenectomy in cervical cancer. In this multicenter, randomized, noninferiority trial, we ...

Teclistamab, a T-cell engager targeting B-cell maturation antigen, showed promise as a rescue therapy in 10 patients with refractory autoimmune diseases and led to clinical and serologic improvemen ...

A 23-year-old woman presented with headache, vomiting, syncope, weight gain, and leg pain. MRI of the head and thighs revealed diffuse hyperintense cystic lesions, and antibodies to cysticerci were ...

This feature about a patient recently treated for C. difficile infection who now needs intravenous antibiotics offers a case vignette accompanied by two essays, one supporting use of oral vancomycin ...