Journal of Nuclear Medicine

From Compassionate Use Toward High-Level Evidence for Radiopharmaceutical Therapy in Recurrent Meningioma: The LUMEN-1 and MOMENTUM-1 Trials

Theranostics and radiopharmaceutical therapies are rapidly transforming the medical landscape, and the neuro-oncology community is observing these developments with great interest. In a field characte ...
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Prognostic Value of Initial Imaging and PSA Change with

Journal of Nuclear Medicine October 2025, jnumed.125.270804; DOI: https://doi.org/10.2967/jnumed.125.270804 ...
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Impact of PSMA PET Staging on Initial Treatment in Newly Diagnosed Prostate Cancer

Journal of Nuclear Medicine October 2025, jnumed.125.270825; DOI: https://doi.org/10.2967/jnumed.125.270825 ...
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Cerenkov Luminescence Imaging of Medical Isotopes

The development of novel multimodality imaging agents and techniques represents the current frontier of research in the field of medical imaging science. However, the combination of nuclear tomography ...
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Biodistribution and Radiation Dosimetry of

Journal of Nuclear Medicine September 2025, jnumed.125.270267; DOI: https://doi.org/10.2967/jnumed.125.270267 ...
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Combining PSMA-Targeted Radiopharmaceutical Therapy with Immunotherapy

PSMA-targeted radiopharmaceutical therapy (RPT) is a standard treatment for metastatic castration-resistant prostate cancer (PCa), exploiting PSMA overexpression to deliver cytotoxic radiation.
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Thyroid Hormone Withdrawal Yields Higher

Journal of Nuclear Medicine September 2025, jnumed.125.270391; DOI: https://doi.org/10.2967/jnumed.125.270391 ...
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177 Lu-PSMA-617 Monotherapy Is Provocative but No Standard of Care for Metastatic Hormone-Sensitive Prostate Cancer

Giri et al. present a case report involving a patient with metachronous low-volume metastatic hormone-sensitive prostate cancer (mHSPC) who declined standard treatments such as androgen deprivation ...
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Multitracer PET to Assess Cardiac Sympathetic Innervation and Vesicular Storage in Lewy Body Diseases

Journal of Nuclear Medicine October 2025, jnumed.125.269840; DOI: https://doi.org/10.2967/jnumed.125.269840 ...
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Influence of Ultra-Low-Dose CT on PET Image Quantification and Visual Assessment

Journal of Nuclear Medicine October 2025, jnumed.124.269188; DOI: https://doi.org/10.2967/jnumed.124.269188 ...
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PET Imaging of the Human Brain with Microvolumetric Spatial Resolution

Journal of Nuclear Medicine September 2025, jnumed.124.268809; DOI: https://doi.org/10.2967/jnumed.124.268809 ...
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Theoretic Criteria for Antibody Penetration into Solid Tumors and Micrometastases

Targeting tumors with antibody-based therapeutics is a complex task presenting multiple kinetic barriers. Antibody internalization and clearance inhibit uptake both in solid tumors, limited by tumor ...