gut.bmj

Pathobiology of liver fibrosis: a translational success story

Correspondence to Scott L Friedman, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave., Room 11-70C, Box 1123, New York, NY 10029-6574, USA; ...
gut.bmj

Gut microbiota modulate T cell trafficking into human colorectal cancer

Objective Tumour-infiltrating lymphocytes (TILs) favour survival in human colorectal cancer (CRC). Chemotactic factors underlying their recruitment remain undefined. We investigated chemokines ...
gut.bmj

Exposure to corticosteroids in pregnancy is associated with adverse perinatal outcomes among infants of mothers with inflammatory bowel disease: results from the PIANO registry

Objective Active inflammatory bowel disease (IBD) during pregnancy may require the use of corticosteroids. The aim of this study was to investigate the impact of in utero corticosteroid exposure on ...
gut.bmj

Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis

Objectives Gastro-oesophageal reflux symptoms are common in the community, but there has been no definitive systematic review and meta-analysis of data from all studies to estimate their global ...
gut.bmj

Fukuoka criteria accurately predict risk for adverse outcomes during follow-up of pancreatic cysts presumed to be intraductal papillary mucinous neoplasms

Correspondence to Dr Suresh T Chari, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA; chari.suresh{at}mayo.edu Objective Fukuoka ...
gut.bmj

The Asia-Pacific Colorectal Screening score: a validated tool that stratifies risk for colorectal advanced neoplasia in asymptomatic Asian subjects

1 Department of Medicine, National University of Singapore, Singapore, Singapore 2 Department of Internal Medicine, National Taiwan University, Taipei, Taiwan 3 Department of Medicine and Therapeutics ...
Gut

CD177+ neutrophils: new drivers of liver regeneration

Liver resection remains the main curative option for many patients with primary and secondary liver malignancies, including ...
Gut

Twenty-four-week anti-PD-1 antibody regimen promoted HBsAg reduction and concurrently enhanced HBV-specific T cell responses in patients with chronic hepatitis B

Background PD-1 blockade has emerged as a promising approach for functional cure of chronic hepatitis B (CHB). Objective This study aimed to evaluate the safety profile of anti-PD-1 antibody (αPD-1), ...
Gut

Revised version global guidelines on diverticular disease of the colon: the Fiesole Consensus report

Introduction Colonic diverticulosis is the most common structural abnormality of the colon in developed countries, with an increasing global prevalence. Approximately 20–25% of affected individuals ...
gut.bmj

CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity

Objective Metabolic reprogramming of tumour cells that allows for adaptation to their local environment is a hallmark of cancer. Interestingly, obesity-driven and non-alcoholic steatohepatitis ...
gut.bmj

Use and abuse of hydrogen breath tests

Correspondence to: Dr M Simrén Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, S-41345 Göteborg, Sweden; magnus.simren{at}medicine.gu.se ...
gut.bmj

Long-term liver-related outcomes and liver stiffness progression of statin usage in steatotic liver disease

19 Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore 24 Center for Digestive Diseases Research and Clinical Translation of Shanghai Jiao Tong University, Shanghai, ...