*Corresponding Author: Nicholas Fidelman, Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Room M-361, San Francisco, CA 94143. E-mail: ...
1Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. 2Guangzhou National Laboratory, Guangzhou, China. 3University of Chinese Academy of Sciences, Beijing, ...
AbstractAge at diagnosis among patients with cancer is a predictor of pathogenic germline variant prevalence, yet age thresholds often misclassify genetic risk. We performed germline sequencing of ...
Abstract:. Eileen M. O’Reilly, MD, a medical oncologist at Memorial Sloan Kettering Cancer Center in New York, NY, whose research focuses on therapies for pancreas cancer, spoke with Cancer ...
Developing drugs against multi-protein complexes is traditionally challenging. In this study, we develop molecular COUPLrs, dual cysteine-reactive small molecules, that can engage complexes across the ...
AbstractSingle-stranded DNA (ssDNA) gaps represent an underappreciated vulnerability that directly shapes therapeutic response in BRCA-deficient models. Current clinical biomarkers remain anchored to ...
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