The San Francisco 49ers downed the Indianapolis Colts on Monday night, and here's who deserves credit and criticism.

It's one thing to respect your elders, but the 49ers' young defensive players were taking it a little too far early on Monday ...

The Indianapolis Colts lose to the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Score updates, ...

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats ...

The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will ...

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the ...

The San Francisco 49ers have been one of the most injured teams thoughout the entire 2025 season. While the team will never ...

Brock Purdy, who threw a career-high five touchdowns, and the 49ers pulled away from the Colts on Monday night for a 48-27 ...

49ers vs Colts final score, results: Brock Purdy throws five touchdowns, 49ers control destiny after win vs. Colts originally ...

Indianapolis Colts kicker Blake Groupe makes a 51-yard field goal. San Francisco 49ers wide receiver Jauan Jennings leaps to ...

In the final game of what has been a wild Week 16, the Indianapolis Colts host the San Francisco 49ers on "Monday Night ...

Close-up of raw Brussels sprouts in a white bowl in Lafayette, Calif., Nov. 16, 2025.