Kickoff from Stade Louis II in Monaco is set for 3 p.m. ET. The latest Monaco vs. Manchester City odds list the visitors as the -235 favorites (risk $215 to win $100) on the 90-minute money line, with Monaco listed as the +550 underdogs.

Aston Villa have picked up 12 points and currently lie in 11th position. In their last encounter, Unai Emery's team were beaten 2-1 by Go Ahead Eagles (UEFA Europa League 2025/26). Manchester City have 16 points to their name this season and occupy 2nd position in the table.

Real Madrid faces Juventus in the UEFA Champions League on Wednesday, Oct. 22, 2025 (10/22/25) at Bernabéu in Madrid, Spain.