Texans head coach DeMeco Ryans is a former 49ers defensive coordinator under Kyle Shanahan, so San Francisco knows how ...

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs.

The 49ers had the ball for only 18 ½ minutes Sunday. It's an apt analogy for Mac Jones, whose time as San Francisco's ...

ESPN BET Sportsbook is owned and operated by PENN Entertainment, Inc. and its subsidiaries ('PENN'). ESPN BET is available in ...

San Francisco quarterback Mac Jones speaks to reporters after the 49ers' 26-15 loss to the Houston Texans on Sunday at NRG ...

Mac Jones has been a massive addition to the San Francisco 49ers this offseason. The team is 4-1 when he starts this season, ...

In Week 8, Mac Jones and the San Francisco 49ers meet the Houston Texans at 1 p.m. ET on Sunday at NRG Stadium. Jones, in his ...

The Texans lost to the Seattle Seahawks 27-19 on Monday night even though Anderson scored the first touchdown of his NFL ...

San Francisco 49ers quarterback Brock Purdy has been ruled out for his team's Week 8 matchup against the Houston Texans amid ...

Brock Purdy's injury update opens a financial opportunity for San Francisco 49ers backup quarterback Mac Jones.

San Francisco 49ers quarterback Mac Jones speaks candidly following the 49ers’ loss to the Houston Texans in Week 8 at NRG ...

San Francisco 49ers QB Mac Jones fired a strike to WR Kendrick Bourne, moving the chains with an 18-yard gain vs. the Texans.