The Buffalo Bills ' home-field advantage will once again be on display on Sunday night with severe weather projected to be on ...

San Francisco 49ers edge rusher Leonard Floyd is excited to face his former Buffalo Bills and ex-teammate Josh Allen in Week ...

Our top pick for the 49ers vs. Bills Week 13 NFL matchup is to bet on the 49ers +6.5 (+100). This betting advice is ...

Buffalo (9-2) will return to action on Sunday night when they host the San Francisco 49ers (5-6). The Bills are perfect ...

Star receiver George Kittle and the San Francisco 49ers meet the Buffalo Bills on Sunday at 8:20 p.m. ET at Highmark ...

The Bills will take on the San Francisco 49ers on Sunday night at Highmark Stadium in Orchard Park. Lake-effect snow bands ...

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...

The Buffalo Bills are fresh off of their bye week heading into a Sunday Night Football matchup with the San Francisco 49ers, ...

Next up for Bills, 9-2, are the beleaguered San Francisco 49ers, 5-6, who limp into Highmark Stadium on Sunday night riding a ...

The Bills return from their bye week with a tough test on Sunday Night Football. Here's a look ahead to the matchup.

Former Bills linebacker Leonard Floyd had a message for Josh Allen and his other former Buffalo teammates ahead of Sunday ...

Buffalo Bills look to extend its six-game win streak as Josh Allen faces an unfamiliar foe in the San Francisco 49ers at ...