BACKGROUND: Oscillatory shear stress (OSS), resulting from disturbed blood flow, is implicated in atherosclerotic plaque formation by incompletely understood mechanisms. This study aims to elucidate ...
This study is led by Dr. Xin Lin (Institute for Immunology of Tsinghua University). They find that the upstream regulator of NF-κB, B-cell lymphoma 10 (Bcl10), is involved in regulating the natural ...
Cascades of signals are transduced when, for example, a hormone meets its receptor, when one cell touches another, or when a lymphocyte contacts its cognate antigen. Many steps in these pathways ...
A team led by UT Southwestern Medical Center researchers has uncovered a molecular pathway that links obesity to widespread inflammation, providing long-sought insight into why obesity increases the ...
BOSTON--(BUSINESS WIRE)--Photys Therapeutics, the pioneer in the development of phosphorylation-inducing chimeric small molecule medicines (PHICS), founded by Longwood Fund and Dr. Amit Choudhary of ...
Phosphorylation of α-synuclein at serine 129 has long been used as a marker of synucleinopathy—p-S129syn accumulates in Lewy bodies, after all. But does this modification have a physiological function ...
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