TLR (Toll-like receptor) signal transduction involves five adaptor proteins. MyD88 (myeloid differentiation primary-response gene 88), MAL (MyD88-adaptor-like protein), TRIF (TIR-domain-containing ...
A key point of control of inflammation is at the level of transcription. In macrophages, which are key orchestrators of the inflammatory response, transcriptional control of inflammation enables the ...