Beyond the active site: A new way to regulate immune enzyme TREX1

The immune system must maintain a delicate balance to defend against harmful threats while avoiding excessive inflammation.

Brain enzyme shapes branched sugar chains linked to nerve health

Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the ...

Metallic markers make direct measurement of protein activity possible

Cells operate on rules not vibes, including when on the precipice of persisting or perishing. Yet, with prior research ...

NASA animation shows exactly how its crewed moon mission will unfold

A NASA video (above) reveals in great detail how its upcoming Artemis II mission is expected to play out. The space agency ...
GeekTyrant

Trailer For Darren Aronofsky’s AI Series ON THIS DAY… 1776 Recreates America’s Origin Story With Human Voice Actors

Filmmaker Darren Aronofsky is experimenting with artificial intelligence through his AI-focused studio Primordial Soup, which has just unveiled the trailer for On This Day… 1776 , an animated ...
Frontiers

Transporters and Drug-Metabolizing Enzymes in Disease and Drug Interactions: Mechanisms, Prediction, and Clinical Impact

Transporters and drug-metabolizing enzymes are critical determinants of drug disposition and response. Beyond their classical roles in pharmacokinetics, ...