Dendritic cells occupy a pivotal role at the nexus of metabolism and immune regulation, employing distinct bioenergetic programmes to calibrate antigen uptake, processing and presentation. In their ...

EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a ...

Cancer immunotherapy is a strategy that turns the patient’s own immune cells into a “search-and-destroy” force that attacks the tumor’s cells. The “search” immune cells are the dendritic cells, which ...

The immune system has evolved to mount immune responses against foreign pathogens and to remain silent against self-antigens. A balance between immunity and tolerance is required as any disturbance ...

Belgian scientists have uncovered new details about how the immune system responds to vaccines. Dendritic cells, which are key immune messengers that help kick-start the body's defenses, show specific ...

Researchers from the lab led by Prof. Joris De Wit (VIB-KU Leuven) have discovered an important clue to how connections between brain cells, known as synapses, mature. These new findings, published in ...

For her Ph.D. at VUB and KULeuven, Aarushi Caro created a kind of systematics for dendritic cells, a special group of immune cells in the fight against cancer. Until now, there was a lot of confusion ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

A new analysis method to measure the propagation of different membrane currents along complex dendritic trees reveals the conditions leading to burst firing in a computational model of place cells.

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...