Catabolism, the breakdown of nutrients, is part of metabolism -- the complex series of chemical reactions that sustain life. Lysine is an important amino acid required for protein synthesis ...

Study: Multi-omic Profiling of Sarcopenia Identifies Disrupted Branched-chain Amino Acid Catabolism As a Causal Mechanism and Therapeutic Target. Image Credit: Kurteev Gennadii / Shutterstock.com ...

Catabolism, the breakdown of nutrients, is part of metabolism—the complex series of chemical reactions that sustain life. Lysine is an important amino acid required for protein synthesis ...

The study focuses on lysine catabolism. Catabolism, the breakdown of nutrients, is part of metabolism — the complex series of chemical reactions that sustain life. Lysine is an important amino acid ...

Zuo and colleagues identify impaired mitochondrial branched-chain amino acid (BCAA) catabolism during sarcopenia. Pathological BCAA accumulation in aged muscle overactivates mTOR and paradoxically ...