Christian McCaffrey and Jordan Mason both landed on IR after the 49ers lost to the Bills in Week 13. Isaac Guerendo will now ...

San Francisco 49ers running back Christian McCaffrey will not need surgery on his injured right knee but he will miss the ...

The San Francisco 49ers plan to place running backs Christian McCaffrey and Jordan Mason on injured reserve after suffering ...

The 24-year-old Guerendo was a fourth-round pick in the 2024 NFL draft. He transferred to Louisville for the 2023 season ...

The San Francisco 49ers running back injured the PCL in his knee, an MRI confirmed Monday. San Francisco plans to place ...

Here's everything you need to know about the 49ers current RB depth chart following injuries to Christian McCaffrey and ...

Jennifer Lee Chan highlights potential external options the San Francisco 49ers could consider after injuries to Christian ...

As the San Francisco 49ers departed Buffalo in the wee hours Monday morning, they were bracing for the possibility that ...

A trying season for the San Francisco 49ers took two more hits after Sunday's loss to the Buffalo Bills. The one-time ...

The 49ers — who were already without Trent Williams, Nick Bosa and Deommodore Lenoir — saw Christian McCaffrey leave their ...

The 49ers lost running back Christian McCaffrey for the season with a knee injury. His backup, Jordan Mason, will also be ...

McCaffrey suffered a PCL injury during Sunday's loss to the Bills, while Mason goes on IR with a high ankle sprain.