AbstractBackground:. EGFR is a known oncogenic driver in colorectal cancer (CRC). The leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) is expressed in CRC stem-like cells and drives ...
JNJ-95437446 is a potential best-in-class EGFR/MET bispecific antibody drug conjugate designed to deliver a cytotoxic payload to tumor cells while leveraging the unique characteristics of amivantamab.
Abstract 7901: Renal cancer early diagnosis using a novel B7-H3 targeted ultrasound contrast imaging
AbstractAim:. Cost-effective or accessible methods to detect kidney cancers, especially those with renal insufficiency, remain elusive. We propose ultrasound molecular imaging (UMI) using microbubbles ...
You do not currently have access to this content.
Background: STK-012 is a first-in-class α/β-IL-2R biased partial agonist designed to drive antitumor activity by selectively stimulating CD25+ antigen activated T cells, while avoiding hallmark IL-2 ...
1Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida.
From molecules to medicine, from proteomics to prevention, the journals of the AACR cover the entire spectrum of cancer research. Please select the journal that is most appropriate for your manuscript ...
*Corresponding Author: Nicholas Fidelman, Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Room M-361, San Francisco, CA 94143. E-mail: ...
1Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. 2Guangzhou National Laboratory, Guangzhou, China. 3University of Chinese Academy of Sciences, Beijing, ...
AbstractProstate cancer frequently metastasizes to bone, marking incurable disease. This progression is driven by an immunologically cold bone tumor microenvironment that fosters resistance to therapy ...
Ming Li Han Liang Jonathan Licht De-Chen Lin Hui-Kuan Lin Piro Lito David Lyden Conor C. Lynch Mathieu Lupien Li Ma Anant Madabhushi Andriy Marusyk Massimiliano Mazzone John D. Minna Lindsay M. Morton ...
Abstract. Advances in cancer prevention, early detection, and treatment have led to substantial improvements in cancer outcomes in the United States over the past several decades. Despite this ...
Results that may be inaccessible to you are currently showing.
Hide inaccessible results