By identifying the critical role the urea cycle plays in its development, his findings could pave the way for new medications to treat this currently incurable disease.

Conducted during his time at Washington University in St. Louis, the study found that these urea cycle defects lead to secondary impairment in the tricarboxylic acid (TCA) cycle, a key pathway for ...

Conducted during his time at Washington University in St. Louis, the study found that these urea cycle defects lead to secondary impairment in the tricarboxylic acid (TCA) cycle, a key pathway for ...

The authors believe that the drug may also be effective for children with urea-cycle disorders and other genetic diseases that lead to increased levels of ammonia by causing mitochondrial ...