How long does prednisone stay in your system? After taking prednisone, it may stay in your system for up to about 22 hours. The half-life of prednisone is 3 to 4 hours in an adult.

Prednisone is a versatile medication — but it has a few potential side effects. Does prednisone cause hair loss? It’s possible, though there’s not much evidence to confirm it.

Long-term use of steroids can lead to numerous side effects, and heartburn is one of them. Here's how they are linked and what you can do.