2 Minute Medicine12d
Switching from ticagrelor to clopidogrel may demonstrate benefit in patients with large body mass index and prior myocardial infarction
A deescalation strategy involving switching from ticagrelor to clopidogrel in patients with acute myocardial infarction (AMI) ...
2 Minute Medicine10d
Evidence gap for acute pain outcomes in opioid use disorder
In this systematic review, evidence for the efficacy of acute pain interventions on individuals with opioid use disorder was ...
2 Minute Medicine5h
Ketorolac may have a role in the perioperative management of aortic dissection
In this randomized clinical trial, the use of ketorolac in patients with Acute Type A Aortic Dissection (aTAAD), was not associated with a significant difference in efficacy or safety. However, it was ...
2minutemedicine.com9d
Music listening may be an effective adjunct for pain control
2. The use of music in the healthcare setting can have negative outcomes depending on the kind of music and if it is used at ...
2 Minute Medicine9d
Merck’s Winrevair: Pulmonary arterial hypertension drug shows success ahead of schedule
Strong positive interim data from an earlier Phase 3 trial has led to early cessation of Merck’s pulmonary arterial ...
2 Minute Medicine6h
Nivolumab plus ipilimumab improves progression-free survival in metastatic colorectal cancer
Progression-free survival was significantly greater in the nivolumab plus ipilimumab group compared to nivolumab alone. 2. Treatment-related adverse events were slightly higher in nivolumab plus ...
2 Minute Medicine8d
Characterization of increased aspiration pneumonia risk in patients with stroke
Aspiration pneumonia in post-stroke patients showed significantly increased 90-day mortality, longer hospital stays, and more ...
2 Minute Medicine8d
Patient values and preferences when treating acute episodic migraine
In this rapid review, patients valued effectiveness for treating pain more highly than other attributes such as avoiding harm and reducing other migraine symptoms. 2. However, avoiding harm was also ...
2 Minute Medicine1d
Less frequent mammography is non-inferior to annual screening for breast cancer survival in women after curative treatment
Less-frequent mammographic surveillance showed a similar recurrence-free interval. Evidence Rating Level: 1 (Excellent) Study ...
2 Minute Medicine1d
4:3 intermittent fasting effective for weight loss among adults with obesity
In this randomized controlled trial, 4:3 intermittent fasting was associated with significantly greater weight loss compared ...
2 Minute Medicine3d
Patient navigation may improve colonoscopy completion following abnormal stool test
In this randomized controlled trial, participants with an abnormal fecal immunochemical test who received patient navigation ...
2 Minute Medicine3d
Low-Dose CT for Lung Cancer Screening in a High-Risk Population
A total of 2% of the eligible population was diagnosed with lung cancer after a positive screen on baseline CT, amounting to a number needed to screen being 49. 2. The sensitivity of the low-dose CT ...