Ohio State's defense is elite, but Julian Sayin could be the program's x-factor in repeating as national champions.

A stunning collapse of the James Franklin era at Penn State has left Ohio State a three-touchdown favorite. The Nittany Lions opened the season ranked No. 2 in the AP poll but have dropped four straight and will be playing their second game under interim coach Terry Smith following Franklin's firing.

Preview the Nov. 1 matchup between the Ohio State Buckeyes and Penn State Nittany Lions with predictions, odds, over/under, spread, betting lines and more.

The Tennessee Volunteers played one of their toughest games in their college football season on Saturday, which was a very intriguing game for the recruits and

Kickoff from Ohio Stadium in Columbus, Ohio, is at noon ET. This spread was much tighter in the early-season lookahead lines, but now the Buckeyes are huge 18.5-point favorites in the latest Penn State vs.

The Big 12 had two teams in the top 10 for the first time in two years and Notre Dame was back in the top 10 after a two-month absence.

Here is a complete guide to listening to Ohio State vs. Penn State, including the start time, TV schedule, and live stream information for the Week 10 college football game.

It’s like watching the Harlem Globetrotters. Without the buckets of confetti. That’s not a criticism. They’re the best team in the country.