Mycobacterium tuberculosis infects the respiratory tract and establishes a complex interplay with the host immune system. Upon inhalation, bacilli are phagocytosed by alveolar macrophages but evade ...

lasma metabolomic analysis in active tuberculosis patients and healthy controls. Cerebral tuberculosis (CTB), a severe and often fatal form of central nervous system (CNS) tuberculosis, poses ...

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that orchestrate the degradation of extracellular matrix components during Mycobacterium tuberculosis infection. In pulmonary ...

A histone acetylome-wide associations study (HAWAS) performed in immune cells from patients with active Mycobacterium tuberculosis infection versus those from healthy controls, has for the first time ...

A more accurate understanding of this pathogenic mechanism could provide a target against the bacterium that caused 1.6 million deaths in 2021, along with 10 million new cases of tuberculosis every ...

Down-regulation of plasma exosome-derived apolipoproteins APOA1, APOB, and APOC1 indicates DR-TB status and lipid metabolism regulation in pathogenesis. Group case-controlled study assessed 17 drug ...

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism - the intrinsic link between metabolism in immune ...