Transcription factors are an essential part of gene expression. Some of these proteins are known as master regulators, and they can have an impact on many different biochemical pathways and processes ...

A new review in Molecular Cancer details how the TEAD family of transcription factors drives cancer, the drugs now targeting ...

A research team has identified a molecular brake on the accumulation of wheat grain proteins that help determine flour ...

Researchers have uncovered a previously hidden layer of complexity in how genes are activated, showing that water molecules play a direct and essential role in one of the most fundamental processes in ...

Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular senescence—a state where cells stop dividing but remain metabolically active.

Single-nucleotide mutation maps and simulations indicate that mutation bias and GC-biased gene conversion largely shape nucleotide composition near human transcription start sites.