Anfinsen, based on his studies of the ribonuclease enzyme, proposed that all the information needed to determine the tertiary structure of a protein is encoded in its amino acid sequence. “It is ...

Intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their ...

Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging.

The result is a three-dimensional Fourier, or electron-density, map of the unit cell, which for the first time reveals the general nature of the tertiary structure of a protein molecule.

To understand how RNA functions, it is essential for scientists to know its 3D structure. Kihara studies protein tertiary structure prediction/comparison, protein-protein docking, protein-ligand ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure ... translation of the genetic code into the correct amino acid sequence of the protein. tRNAs are highly ...