Transforming growth factor beta (TGF-β) encompasses a family of three related cytokines that orchestrate the cellular and molecular events of wound repair. Upon injury, TGF-β is released from ...

Bone remodelling is a dynamic process that balances resorption and formation to preserve skeletal integrity. Transforming growth factor beta (TGF-β) comprises a family of secreted cytokines that ...

The central image depicts currently used strategies for clinical targeting of TGF-β. Below are methods applicable from preclinical screening to clinical practice, including using humanized mouse ...

When it comes to cancer metastasis, it takes two to tango. That was one of the key findings of a new study led by researchers at Memorial Sloan Kettering Cancer Center (MSK): The TGF-beta and RAS ...

Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and development. The study is published in the journal Nature Communications. The ...

A phase II study of agenT-797 (invariant natural killer T-cells), botensilimab (Fc-enhanced CTLA-4 inhibitor) and balstilimab (anti-PD-1) in patients with advanced, refractory gastroesophageal ...

We're going to get started. Thank you, everyone, for joining us here in Berlin, and there are many more of you that are online. Welcome to the solid tumor update that we're having at ESMO 2025. We're ...

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