Caption: Structure of a HIV capsid (Left) Central slice view of a HIV virus-like particle with pore-forming toxin on the membrane (Middle) Atomic model of a HIV capsid (Right) Density map of HIV ...
To become infectious, HIV has to undergo a maturation process, which involves a rearrangement of the matrix proteins (red). In an immature virus particle, the matrix proteins form a lose lattice ...
When we know the structure of a protein, we can attempt to design small drug molecules to bind to it and block its function. The power of this approach has been shown in the battle against HIV and ...
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HIV and the Brain: Unveiling the Hidden Threat of AIDS DementiaHIV/AIDS impacts multiple organ systems, including the brain and nervous system. Most individuals are unaware that HIV spreads to the brain early in the illness process. HIV encephalopathy, a ...
Researchers at the Vaccine Research Center (“VRC”) have determined the three-dimensional structure of the HIV-1 Envelope trimeric ectodomain (“Env”), comprised of three gp120 and three ...
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