AMES, Iowa — Over the last 20 years, researchers in biology and medicine have created Boolean network models to simulate complex systems and find solutions, including new treatments for colorectal ...

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that ...

Gene Regulatory Networks (GRNs) reveal how genes regulate each other, offering insights into complex biological systems. Traditional GRN inference, based on bulk RNA sequencing, reflects average gene ...

The majority of disease-associated genetic variants are thought to have regulatory effects, including disruption of transcription factor (TF) binding and alteration of downstream gene expression.

A newly published study provides guidance for building accurate mathematical models for gene regulatory networks. Over the last 20 years, researchers in biology and medicine have created Boolean ...