The majority of disease-associated genetic variants are thought to have regulatory effects, including disruption of transcription factor (TF) binding and alteration of downstream gene expression.

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that ...

Findings from research into bacterial cells’ behavior done by scientists at Northwestern University and the University of Texas-Southwestern could have implications for how infections are treated.

A newly published study provides guidance for building accurate mathematical models for gene regulatory networks. Over the last 20 years, researchers in biology and medicine have created Boolean ...

Scientists have uncovered evidence supporting a mechanism in which transposable elements (TEs), once considered ...