NFL Week 10 odds, picks, predictions, TV channel, streaming information for Thursday Night Football game between Las Vegas Raiders and Denver Broncos.

Week 10 of the NFL season kicks off with an AFC West showdown on Thursday night as the Denver Broncos host the Las Vegas Raiders. And that's just the start of the division rivalry slate this week.

Spread: Broncos -10 Moneyline: Broncos -520, Raiders +390 O/U: 42.5 Spread: Colts -6.5 Moneyline: Colts -325, Falcons +260 O/U: 48.5 Spread: Buccaneers -2.5 Moneyline: Buccaneers -135, Patriots +114 O/U: 48.5 Spread: Bills -8.5 Moneyline: Bills -410, Dolphins +320 O/U: 50.5 Spread: Ravens -3 Moneyline: Ravens -175, Vikings +145 O/U: 48.5

NFL Week 10 betting spreads, lines, point totals for every game on NFL Week 10 schedule, with odds for favorites and underdogs in each NFL matchup.

Get the opening NFL Week 10 odds with point spreads, Over/Unders, and football moneylines for every matchup starting on Nov. 6, 2025.

The Chargers have been generous to tight ends all season, too. They rank bottom 10 in receptions allowed to the position. With the Steelers offense showing improved balance, Freiermuth profiles as a steady low-end TE1/high-end TE2.

The latest NFL Power Rankings ahead of Week 10 take a look at the biggest risers and fallers around the league, with a new team at #1.

The Texas Tech Red Raiders are visiting the Kansas State Wildcats in a pivotal Big 12 Conference matchup. Follow along for live updates.