Gene duplication is the primary mechanism by which new genes emerge. Models and empirical studies have shown that paralogous genes are maintained because of dosage benefits, the partitioning of ...
Multiple myeloma (MM) is the second most common of all hematological malignancy1, with main symptoms such as hypercalcemia, renal impairment, anemia, bone destruction, etc1. It usually starts from ...
This is a single-institution retrospective cohort analysis comprising patients seen in the Department of Clinical Genetics and consented to the Risk Assessment Program (RAP) Registry who were ...
A large international genome-wide association study identified five new genetic variants and 22 high-probability risk genes linked to irritable bowel syndrome (IBS), narrowing the biological pathways ...
The underlying mechanism of the transformation of a normal cell into a cancerous cell lies in the acquisition of faults in ...