This is a preview. Log in through your library . Abstract Long-term potentiation (LTP) is a cellular mechanism of learning and memory that results in a sustained increase in the probability of ...

α-Synuclein (α-Syn) is a presynaptic protein primarily associated with Parkinson’s disease and other neurodegenerative diseases. The cholesterol content in SV membranes regulates α-Syn binding to ...

The synaptotagmin protein family has been studied by neuroscientists for decades. However, most isoforms lack well-defined functions. Now, researchers have identified a crucial, presynaptic role for ...

Phosphorylation of α-synuclein at serine 129 has long been used as a marker of synucleinopathy—p-S129syn accumulates in Lewy bodies, after all. But does this modification have a physiological function ...

α-synuclein (α-syn) is a small presynaptic protein linked to the pathogenesis of Parkinson’s disease (PD) and related disorders, collectively called synucleinopathies. Phosphorylation of α-syn at ...

In a study published in Science on October 17, a team led by Prof. BI Guoqiang from the University of Science and Technology of China/Shenzhen Institutes of Advanced Technology of the Chinese Academy ...