The first study to examine the effects of whole-chocolate consumption on ex vivo platelet function has shown that dark chocolate acutely reduces collagen-stimulated platelet aggregation and reduces ...

Platelets are expert at patching up leaks in blood vessels, but could they go overboard and seed amyloid-β plaques as well? As reported in Science Signaling on May 24, Aβ monomers bind integrin ...

When cancer cells and platelets mix, the risk of metastasis and cancer-related deep vein thrombosis (DVT) and pulmonary embolism (PE) increases, but a small, proof-of-concept study suggests that the ...

A recently described hemorrhagic disorder characterized by defective platelet aggregation induced by collagen and epinephrine appears to be caused, in part, by the same abnormality induced by aspirin ...

Bleeding because of impaired platelet function is a major side effect of the Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib. We quantitatively assessed ristocetin-induced platelet aggregation ...

Psm2, one of the pyrrolidinoindoline alkaloids isolated from whole Selaginella moellendorffii plants, has shown a potent antiplatelet activity. In this study, we further evaluated the antiplatelet ...

Abnormalities of platelet function in some patients with primary, but sporadic, disorders of hemostasis have been attributed to impaired release of platelet adenosine diphosphate (ADP). This defect ...

Assessment of feasibility and willingness of former heavy smokers to participate in chemoprevention trials to prevent lung cancer. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I.

Moderate alcohol consumption is believed to reduce mortality from cardiovascular disease. Binge drinking, on the other hand, is known to increase mortality from all causes. Recent findings indicate ...

A new study created a score to identify patients with platelet hyperreactivity and risk of related, future cardiovascular disease. Platelets are circulating cell fragments known to clump up and form ...

Platelets are circulating cell fragments known to clump up and form blood clots that stop bleeding in injured vessels. Cardiologists have long known that platelets can become "hyperreactive" to cause ...