A team led by UT Southwestern Medical Center researchers has uncovered a molecular pathway that links obesity to widespread ...

The authors present convincing data to validate abscisic acid-induced dimerisation to induce a synthetic spindle assembly checkpoint (SAC) arrest that will be of particular importance to analyse ...

Cascades of signals are transduced when, for example, a hormone meets its receptor, when one cell touches another, or when a lymphocyte contacts its cognate antigen. Many steps in these pathways ...

Plant phototropism—directional growth in response to light—serves as a key adaptive mechanism, optimizing photosynthesis and development. Central to this process is phototropin 1 (phot1), a primary ...

Multiple studies have demonstrated the memory-enhancing effects of melatonin and its derivatives in animal models. It is also known that the formation of both short- and long-term memories require the ...

Photys Therapeutics has debuted with $75 million in series A financing to develop phosphorylation-inducing chimeric small molecules (PHICs) to treat disease. PHICs are two-ended molecules that draw ...

BOSTON--(BUSINESS WIRE)--Photys Therapeutics, the pioneer in the development of phosphorylation-inducing chimeric small molecule medicines (PHICS), founded by Longwood Fund and Dr. Amit Choudhary of ...

The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich conditions, producing massive amounts of lactate that accumulate in the tumor ...

Phosphorylation of α-synuclein at serine 129 has long been used as a marker of synucleinopathy—p-S129syn accumulates in Lewy bodies, after all. But does this modification have a physiological function ...