Scientists at VIB and KU Leuven have identified the oxygen sensor PHD1 as a potential target for the treatment of brain infarction (ischemic stroke). Despite (minor) improvements in stroke treatment, ...
Scientists have identified the oxygen sensor PHD1 as a potential target for the treatment of brain infarction (ischemic stroke). Despite (minor) improvements in stroke treatment, stroke remains the ...
HIF prolyl hydroxylases (PHD1–3) are oxygen sensors that regulate the stability of the hypoxia-inducible factors (HIFs) in an oxygen-dependent manner. Here, we show that loss of Phd1 lowers oxygen ...
Blocking the PHD1 oxygen sensor hinders the activation of p53, a transcription factor that aids colorectal cancer (CRC) cells in repairing themselves and thus resisting chemotherapy, scientists have ...
Leuven, Belgium - When a blood vessel clogs up, a localized deficiency of oxygen results, causing the surrounding tissue to die. However, working with mice, VIB scientists connected to the Katholieke ...
Clinical significance of serum claudin-7 levels in patients with colorectal cancer. Use of FLIM histology-based HER2-HER3 heterodimer quantification and a Bayesian latent class proportional hazards ...
Scientists at VIB and KU Leuven have shown that blocking the PHD1 oxygen sensor hinders the activation of p53, a transcription factor that aids colorectal cancer (CRC) cells in repairing themselves ...
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