Multi-dimensional separations are essential to obtain a precise and detailed view of the content of complex proteomics samples in both targeted (quantitative) and discovery workflows, and since the ...

Understanding the proteome is a fundamental challenge of biology. Any large-scale, proteomics-related study will necessitate the ability to reliably identify as many components of the proteome as ...

Innovations in mass spectrometry (MS) technology have enabled researchers to uncover previously unexplored parts of the proteome over the years, assisting the discovery of new drugs and pushing the ...

What is the mechanism of PASEF? PASEF traps precursor ions eluted during liquid chromatography in a tunnel, where they are accumulated and ordered depending on their collisional cross-sectional area ...

>8000 quantified cell lysate proteins with 40-minute gradients >5000 quantified cell lysate proteins with 4.8-minute separations on Evosep One >5000 quantified proteins in just 10 ng of cell lysate ...

The accessibility of blood, and hence plasma, from patients makes it a popular source of samples for clinical research. Routine quantitative analysis on these samples is primarily conducted using ...