The key to discovering better treatments for chronic lung diseases sits with the p73 gene, scientists believe. They found that this gene is the master regulator of a cell type that is responsible for ...
Celltrion announced on June 11 that it presented preclinical results for its antibody-drug conjugate (ADC) new drug candidate, 'CT-P73', at the ongoing 'World ADC Asia Summit' held at the Grand Hyatt ...
Healthy aging relies on proper function of the transcription factor p53. Known as “guardian of the genome,” this protein regulates key physiological events such as the cell cycle, DNA repair, and ...
Ki-67 is a Luminal B marker that identifies a high-risk subgroup in hormone receptor positive and node negative breast cancer No significant financial relationships to disclose. This is an ASCO ...
The P73 gene is a homologue of the P53 tumor suppressor. Owing to its structural similarity with p53, p73 was originally considered to have tumor suppressor function. However, the discovery of ...
Schematic illustrating the effects of p53C and M237I in driving the conversion of p63C and p73C droplets into amyloid aggregates at physiologically relevant temperatures. Heparin prevents the ...
Rising global air pollution and increasing smoking prevalence in many developing nations will likely lead to a growing incidence of lung diseases such as chronic obstructive pulmonary disease (COPD), ...
The process of producing high-quality, fertile sperm requires many steps. A study in The Journal of Cell Biology shows how the transcription factor p73 promotes this process by regulating the ...
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