NFL Week 10 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Los Angeles Rams and San Francisco 49ers.

The Saints only possessed the ball for 16:07 on Sunday, meaning L.A. won the time of possession battle by over 27 minutes. It's also the most time of possession the Rams have had in a game in the McVay era (since 2018), according to nflverse data.

You've seen the model's best bets for New Orleans Saints vs. Los Angeles Rams. Now, get against the spread, total and money-line picks for every Week 9 NFL game here, all from the model that's simulated every game 10,000 times.

It would have been disingenuous for the Los Angeles Rams to fall too far in the Week 9 power rankings following their Week 8 bye. The team actually "won" their week off, thanks to losses by other NFC contenders, made a small trade for a starting cornerback and got healthier with the impending returns of Puka Nacua and Rob Havenstein.

Watch full game highlights from the Los Angeles Rams vs. New Orleans Saints game in Week 9 of the 2025 NFL season.

Alvin Kamara and the New Orleans Saints will face Puka Nacua and the Los Angeles Rams in Week 9 of the NFL season on Sunday.

As such, the Rams actually have the fifth-oldest roster in the NFL this season, weighted by snap share, according to ESPN's Bill Barnwell.

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INGLEWOOD, Ca. The Los Angeles Rams defense were called upon to take on Kellen Moore's New Orleans Saints offense. After already battling against them in a joint practice before the season, I posed five questions the defense must answer on Sunday. Here are their answers.