During tissue development, gradients of secreted signaling molecules known as morphogens provide cells with positional information. The mechanisms underlying morphogen spreading have been widely ...

Cell fate specification and patterning within a tissue, are achieved by positional information provided by the concentration gradients of a group of signaling molecules termed morphogens 1. These ...

Tissue patterning is an important process during embryo formation, which ensures that groups of cells are arranged in an appropriate manner that allows them to function properly. Tissue patterning is ...

Biologists have discovered new mechanisms that control how proteins are expressed in different regions of embryos, while also shedding additional insight into how physical traits are arranged in body ...

In a recent study published in Nature Communications, researchers examinea the effects of temporal morphogen gradient during neural induction (NI) on the formation of brain organoids. Study: Temporal ...

Morphogens are molecules that travel from cell to cell in order to pattern tissues in the embryo. These molecules are important not only for the embryo during development, but also for the adult ...

Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new Yale-led study shows that, early in development, molecular “traffic cops” known ...

Morphogens are signaling molecules that are vital for cell differentiation. These molecules directly influence cell differentiation, inducing specific cellular responses in relation to their ...

Recent advances that have enabled the growth of tissue cultures into organoids and embryoids have heightened interest as to how tissue growth is controlled during the natural processes of embryo ...

Cells producing noise in the Wnt morphogen gradient are sensed by neighboring cells through E-cadherin and then eliminated through the Smad-ROS (reactive oxygen species) axis. Disclaimer: AAAS and ...