Mood symptoms alone do not account for the extent of disability associated with MDD. 12 Cognitive impairment, 1 of the 9 core symptoms of MDD (see Table 1), is significantly associated with impaired ...

A multi-center clinical trial is now enrolling patients to test whether surgically implanted electrodes delivering continuous electrical pulses to a specific brain region can relieve depression that ...

The largest and most ethnically diverse study of its kind has identified 697 genetic variants linked to major depressive disorder (MDD). The research also highlights potential therapies for ...

Depression and seasonal affective disorder (SAD) share similar symptoms, but depression can occur at any time of the year, while SAD follows a recurring seasonal pattern. For a SAD diagnosis, a person ...

A controlled clinical trial suggests a fast-acting psychedelic approach may reduce depressive symptoms, but researchers stress careful interpretation and the need for larger long-term studies. Study: ...