Cas12i is a newly identified member of the functionally diverse type V CRISPR-Cas effectors. Although Cas12i has the potential to serve as genome-editing tool, its structural and functional ...

Fig. 3: Long-range R-loop dynamics are governed by the 6 bp periodicity of the crRNA–target strand hybrid. After locking, the R-loop length became tightly constrained around 26 bp for the T6, 30 bp ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...

If you got into a spaceship and traveled long enough and fast enough, could you eventually loop back to where you started? Assuming you don't accidentally collide with another planet or star, and that ...