Environmental stressors such as radiation, pH shifts, temperature variations, and electromagnetic fields can trigger intracellular oxidative stress, upregulating voltage-gated ion channel (VGIC) gene ...

Neuroinflammation is now recognized as a central driver instead of being merely a consequence of many neurological diseases, including neurodegenerative ...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers at Weill ...

Nervous systems function via electrical excitability mediated by ion channels, an ancient preneuronal feature that many cells use to rapidly adjust behavior. Here, we systematically study the ...

They are literally channels for communication: Pore-forming proteins in living cells, termed ion channels, are embedded in the outer membrane of almost all cell types and play a crucial role in the ...

Researchers have discovered how an ion channel in the brain's neurons has a kind of 'molecular memory', which contributes to the formation and preservation of lifelong memories. The researchers have ...

Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed. Although biophysicist Bernard Katz from ...

A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the ...