To pump the hydrogen ions into the stomach, the protein first needs to bind to a potassium ion (K +). Similar proteins typically bind two such potassium ions to trigger the pump mechanism. But H + /K ...

Nagoya University researchers and colleagues have improved understanding of the molecular mechanisms of a key protein that makes the stomach acidic. Their findings, published in the journal Nature ...

For gastric-acid reduction, the potassium-competitive acid blocker tegoprazan is associated with a lower risk of kidney function decline compared with the proton pump inhibitor esomeprazole. Use of a ...