Hepatic stellate cell (HSC) activation on liver injury facilitates fibrosis. Hepatokines affecting HSCs are largely unknown. Here we show that hepcidin inhibits HSC activation and ameliorates liver ...
A research team from United Kingdom described the use of radioimmunoassay to demonstrate and measure hepcidin-25 in various biological fluids. They provided evidence for the first time of the presence ...
Long-term protective effects of the angiotensin-receptor blocker telmisartan on epirubucin-induced inflammation, oxidative stress, and myocardial dysfunction. Hepcidin 1st tertile 6/47 (13%) 4/41 (10% ...
June 1, 2012 (Paris, France) — Vitamin D supplementation is safe and economic for patients with chronic kidney disease (CKD); it can also decrease the need for erythropoietin-stimulating agents and ...
Polycythemia vera is a chronic myeloproliferative neoplasm characterized by erythrocytosis. Rusfertide, an injectable peptide mimetic of the master iron regulatory hormone hepcidin, restricts the ...
New research highlights how elevated levels of the iron-regulating hormone hepcidin contribute to psoriasis by driving skin cell proliferation and inflammation, offering fresh avenues for therapy.
The importance of recognizing that iron is phlogistic . . . is that such recognition helps us to understand that in giving iron to patients with inflammatory joint disease, we supply the means for ...
Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2-3% of the global population. The condition is characterized by red, scaly ...