In a study published in Applied Physics Letters, researchers at Tohoku University introduced a mild fluorination method to address graphene's zero-bandgap limitation. Characterization of the Gr and ...
Researchers at GlaxoSmithKline report a greener and lower-cost route to chiral fluorolactams that is suitable for scale up. The incorporation of fluorine into APIs continues to be a key approach to ...
Fluorination has emerged as a cornerstone of modern organic synthesis, driven by the profound influence of fluorine on molecular properties such as lipophilicity, metabolic stability and binding ...
Catalytic fluorination in heterogeneous systems has become a cornerstone of modern synthesis, enabling the efficient insertion or removal of fluorine atoms under controlled conditions. The ...
(Nanowerk News) Researchers from Tohoku University and collaborators have developed a weak fluorination strategy to address the zero-bandgap limitation of graphene. The findings are published in ...
Safer fluorinating reagents and access to GMP fluorination capabilities remain challenges in API synthesis. Due to its high ionization potential, electron affinity, and electronegativity, fluorine is ...
Fluorination of therapeutic agents is a widely used strategy in the pharmaceutical industry. It improves a drug’s molecular properties, such as drug-target interactions, bioavailability, and ...
Tasked with improving the biological profile of drug candidates, medicinal chemists treasure reactions that easily slip a fluorine atom onto a molecule. That’s because the addition of this little ...
A novel chemoenzymatic method can add fluorine atoms to natural compounds. The method uses an enzyme that acts as a gatekeeper for precursors and designs a pinch of precursor tolerance to create a ...
A coalition of food safety and agricultural groups are asking the Environmental Protection Agency to ban the use of fluorinated high density polyethylene and polypropylene containers in pesticide ...
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